Press release: Record low for sales of antibiotics for use in animals

Sales of antibiotics for use in animals in the UK have fallen to their lowest level since records began, exceeding a government target to combat the threat of antibiotic resistance (AMR) two years early.

A Defra report released today shows sales of antibiotics for use in food-producing animals dropped by 27%, from 62 mg/kg in 2014 to 45mg/kg in 2016, surpassing a government target of 50 mg/kg set following recommendations in the 2016 O’Neill Review on Antimicrobial Resistance.

Antibiotic resistance is a major threat to modern medicine with estimates suggesting it could be responsible for ten million deaths per year by 2050 and cost the global economy $100 trillion.

In 2013 the UK government launched a strategy to reduce the development and spread of antibiotic resistance in animals and humans. As part of the strategy the government has provided expert advice to the farming industry and veterinary profession, encouraging more responsible use of antibiotics to safeguard them for the future.

Defra Minister for Rural Affairs and Biosecurity, Lord Gardiner, welcomed the report’s findings:

The UK is at the forefront of global efforts to tackle antibiotic resistance. The fact we have overtaken our target two years ahead of schedule demonstrates our commitment to preventing the inappropriate use of antibiotics and shows our approach is working.

Our farmers and vets must be commended for setting an excellent example for others around the world to follow, upholding the UK’s position at the forefront of international efforts to keep antibiotics available for future generations.

Now we must continue making progress and set our sights on reducing use even further. Ambitious specific reduction targets in different sectors will be yet another positive step towards safeguarding antibiotics.

Sales of all the highest-priority antibiotics – considered critically important for human health – have also dropped, accounting for less than 1% of all antibiotics sold for use in animals in 2016. This includes an 83% reduction in sales of Colistin.

The UK’s Chief Veterinary Officer, Nigel Gibbens, said:

These results are immensely positive to see and show the combined efforts of vets and farmers to reduce antibiotic use are paying off. Vets are taking accountability for their prescribing decisions and farmers are investing in disease prevention.

We need solidarity across the profession; no veterinary professional must offer an easy route to access antibiotics where they are not justified. Tackling antibiotic resistance requires a commitment across all areas of animal health, together with work on human use by colleagues in the medical professions, and our work together to tackle the issue at global level.

The UK’s Chief Medical Officer, Professor Dame Sally Davies said:

Drug resistant superbugs are not just a problem confined to human health—it is an issue that spans humans, animals and the environment, so we must take a One Health approach to address it. If we act in isolation, we will fail.

This is a commendable achievement from our agricultural and veterinary sector to reduce the inappropriate use of antibiotics. It shows the entire world what can be done when we join forces and work with focus and passion.

But we cannot rest on our laurels. This progress demonstrates the commitment is there, but we need to build on this momentum and continue to do more, in every sector, and in every country, to stay ahead of superbugs.

Everyone working with animals has a role to play, together with those in the medical profession, in the global fight against antibiotic resistance to monitor use and reduce it wherever possible. Good farm management, biosecurity and animal husbandry systems are vital to achieve this.

Later today a task force established by the industry alliance Responsible Use of Medicines in Agriculture (RUMA) will publish robust targets on antibiotic use to show how each farming sector will build on the excellent progress made to date.

Further information

• Sales of antibiotics for use in animals in the UK have fallen to their lowest level since data were first published by the Veterinary Medicines Directorate in 1993.
• The UK Veterinary Antibiotic Resistance and Sales Surveillance (VARSS) report is published annually by Defra’s Veterinary Medicines Directorate. The report provides the previous year’s data on the quantity of authorised antibiotics for use in animals sold throughout the UK, and results from surveillance programmes looking at antibiotic resistance in animals. The 2016 VARSS report will be available at 11am on Friday 27 October.
• As well as the overall reduction, the report shows a further drop in sales of the highest priority antibiotics that are critically important for humans. Sales of these accounted for less than 1% of all antibiotics sold for use in animals in 2016. This included an 83% reduction in the use of Colistin, an antibiotic of last resort for use in people. Colistin use is now at from an already very low level of use, 0.02mg/kg, putting it considerably below the European Medicines Agency’s target of 1mg/kg.
• RUMA (Responsible Use of Medicines in Agriculture) is an agricultural and food industry alliance which promotes responsible use of medicines in farm animals. It established a Task Force in December 2016 to identify meaningful objectives to reduce, refine or replace antibiotic use in all UK livestock sectors.